Drug Study On Buscopan

Drug Study on Buscopan

Generic Name: Hyoscine ButylBromide

Brand Name: Buscopan

Classification: Belladona alkaloid, antimuscarinic

Indication & Dosages:

Spastic states

Adults: 0.4 to 0.8 mg P.O.

Delirium, preanesthetic sedation and obstetric amnesia with analgesics

Adults: 0.3 to 0.65 mg I.V., I.M., or subcutaneously. Dilute solution with sterile water for injection before giving I.V.

Children: 0.006mg/kg I.V., I.M., or subcutaneously. Maximum dose, 0.3 mg. Dilute solution with sterile water for solution before giving I.V.

To prevent nausea and vomiting from motion sickness

Adults: One Transderm-Scop, formulated to deliver 1mg scopolamine over 3 days, applied to the skin behing the ear at least 4 hours before antiemetic is needed. Or, 0.3 to 0.65 mg hydrobromide I.V., I.M. or subcutaneously. Or, 0.25 to 0.8 mg P.O. 1 hour before exposure to motion. Further doses of 0.25 to 0.8 mg may be given t.i.d., p.r.n.

Children: 6 mcg/k or 200 mcg hydrobromide I.V., I.m., or subcutaneously

Mode of Action:

Inhibits muscarinic actions of acetylcholine on autonomic effectors